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Addison Tarde Espanola 2012 - They know that no matter how pretty you are, how much you love them and how much they love you, there will always be someone out there who's prettier, smarter, younger, fatter, skinnier, more talented, Â [..]Role of Cdc2-cyclin B and Scc2-Scc4 in a new form of apses in Saccharomyces cerevisiae.
The budding yeast Saccharomyces cerevisiae is generally considered to have two distinct types of asexual reproduction: mitotic, which involves true cell division, and meiotic, which does not. However, in some circumstances it is possible for budding yeast to undergo division without chromosome separation. This form of asexual reproduction, termed endoreplication, involves multiple rounds of nuclear DNA replication and, as a result, the resulting nucleus contains a single large DNA mass. We have investigated the molecular basis of endoreplication in budding yeast. We show that the Scc2-Scc4 complex (scs complex), a member of the conserved SKI complex, is required for endoreplication. In addition, we show that the Cdc2-cyclin B complex is also required. We also demonstrate that the scs2-scc4 mutant is similar to a sec mutant, in that the scs2-scc4 mutant is a new form of sec mutant and is dependent on the Sfi1-Sfi2 kinase (SIF kinase).Chlorinated hydrocarbon insecticides: an update of their effects on reproductive function.
Chlorinated hydrocarbon insecticides such as DDT, dieldrin, lindane, and aldrin were first developed during World War II and have subsequently been used in agricultural and urban pest control. In laboratory experiments, DDT and its metabolites have been shown to act through multiple mechanisms to produce many biological effects. These chemicals act as estrogen agonists or antagonists and can have effects on the reproductive system of both males and females. Chlorinated hydrocarbons also act as cocarcinogens, mutagens 0b46394aab